Invitrogen™ PDE3A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA532972

Product Code. 13484639

Description

Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey (94%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least 5 major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).

Specifications

• Antigen: PDE3A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDE3A
• Gene Alias: A930022O17Rik; C87899; cAMP phosphodiesterase, myocardial cGMP-inhibited; CGI-PDE; CGI-PDE A; CGI-PDE-A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A; cGMP-inhibited phosphodiesterase; cyclic GMP-inhibited phosphodiesterase A; cyclic nucleotide phosphodiesterase; HTNB; PDE3A; phosphodiesterase 3A; phosphodiesterase 3A, cGMP inhibited; phosphodiesterase 3A, cGMP-inhibited; RNPDE3A
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5139
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.27 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q14432
• Gene Symbols: PDE3A
• Immunogen: Synthetic 19 amino acid peptide from near N-terminus of human PDE3A.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG