Invitrogen™ PDE2A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA570211

Product Code. 15818623

Description

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%.

PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase (PDE) and three isoforms of PDE2A have been reported (PDE2A1, PDE2A2 and PDE2A3) which arise from a single gene by alternative splicing events. PDE2A can degrade both cAMP and cGMP, but degrades cGMP with greater efficacy. PDE2A is expressed in a variety of tissue types, with greatest expression in the brain, where it is localized in the cerebellum and neocortex. PDE2A has been implicated in penile erectile dysfunction and in the regulation of fluid and inflammatory cell transport across the endothelial cell barrier.

Specifications

• Antigen: PDE2A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDE2A
• Gene Alias: c-GMP stimulated phosphodiesterase; cGMP-dependent 3',5'-cyclic phosphodiesterase; cGMP-stimulated cyclic nucleotide phosphodiesterase; cGMP-stimulated phosphodiesterase 1; cGMP-stimulated phosphodiesterase 2; cGMP-stimulated phosphodiesterase 4; cGSPDE; CGS-PDE; cyclic GMP stimulated phosphodiesterase; cyclic GMP-stimulated phosphodiesterase; cyclic nucleotide phosphodiesterase; cyclic nucleotide phosphodiesterase 2a; Pde2; Pde2a; PDE2A1; Pde2a2; PED2A4; phosphodiesterase 2A; phosphodiesterase 2A, cGMP-stimulated
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 81743
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q01062
• Gene Symbols: PDE2A
• Immunogen: synthetic peptide corresponding to a region of rat PDE2A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG