Invitrogen™ PDE1B Monoclonal Antibody (5C4A3)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA517147

Product Code. 15338090

Description

MA5-17147 targets PDE1B in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human and Rat samples. The MA5-17147 immunogen is purified recombinant fragment of human PDE1B (amino acids: 370-536) expressed in E. Coli. MA5-17147 detects PDE1B which has a predicted molecular weight of approximately 61.4kDa.

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: PDE1B
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q01064, Q01066
• Gene Symbols: Pde1b
• Immunogen: Purified recombinant fragment of human PDE1B (amino acids: 370-536) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 5C4A3
• Conjugate: Unconjugated
• Gene: Pde1b
• Gene Alias: 63 a Cam PDE; 63 a Cam-PDE; 63 kDa Cam-PDE; anti-oxidant protein 2; Aop2; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; calmodulin-stimulated phosphodiesterase PDE1B1; Cam PDE 1B; Cam PDE1B; cam-PDE 1B; cyclic nucleotide phosphodiesterase (CaM-PDE); EGK_03739; epididymis secretory sperm binding protein Li 79p; HEL-S-79p; PDE 1B; Pde1b; Pde1b1; PDES 1B; PDES1B; Phosphodiesterase; phosphodiesterase 1B; phosphodiesterase 1B, Ca2+calmodulin dependent; phosphodiesterase 1B, Ca2+-calmodulin dependent; phosphodiesterase 1B, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase 1B, calmodulin-dependent; phosphodiesterase 1B1 Ca2+-calmodulin dependent 63 kDa; phosphodiesterase 1B1, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase IB calmodulin-dependent; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 29691, 5153
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid