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  6. Invitrogen™ PDCD6 Recombinant Mouse Monoclonal Antibody (K92068_2D10)

Invitrogen™ PDCD6 Recombinant Mouse Monoclonal Antibody (K92068_2D10)

Product Code. 30829621
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30829621 50 μL
30825565 100 μL
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Product Code. 30829621 Supplier Invitrogen™ Supplier No. MA565889

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Description

Mouse Recombinant Monoclonal Antibody

Immunogen sequence: GAGPGPAAGA ALPDQSFLWN VFQRVDKDRS GVISDTELQQ ALSNGTWTPF NPVTVRSIIS MFDRENKAGV NFSEFTGVWK YITDWQNVFR TYDRDNSGMI DKNELKQALS GFGYRLSDQF HDILIRKFDR QGRGQIAFDD FIQGCIVLQR LTDIFRRYDT DQDGWIQVSY Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%, Pig - 98%, Cynomolgus monkey - 99%.

An increased intracellular Ca2+ concentration induces apoptotic cell death. Transiently elevated Ca2+ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis. ALG-2 (for apoptosis-linked gene 2) is a Ca2+ -binding protein that participates in regulatory events occuring late in the apoptotic program and where several death signals converge. ALG-2 is a protein expressed in normal brain, and to a greater extent in ischemic brain. The ALG-2 protein contains five EF-hand-like motifs and shares homology with members of the penta EF-hand family, which includes Calpain small subunits sorcin and Grancalcin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PDCD6
Applications Immunohistochemistry (Paraffin)
Classification Recombinant Monoclonal
Clone K92068_2D10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.5% BSA, 50% glycerol and 0.09% sodium azide
Gene Pdcd6
Gene Accession No. O75340
Gene Alias Alg2; alg-2; ALG-257; Apoptosis-linked gene 2 protein; Apoptosis-linked gene 2 protein homolog; AV299538; MA-3; PDCD6; PEF1B; PMP41; probable calcium-binding protein ALG-2; programmed cell death 6; programmed cell death protein 6; PS2
Gene Symbols Pdcd6
Host Species Mouse
Immunogen Recombinant human PDCD6 (aa 11-180).
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10016
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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