Invitrogen™ PDCD10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA549709

Product Code. 15603645

Description

The antibody detects endogenous level of total PDCD10 protein.

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

• Antigen: PDCD10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pdcd10
• Gene Alias: 2410003B13Rik; apoptosis-related protein 15; CCM3; Cerebral cavernous malformations 3 protein; MGC1212; MGC24477; PDCD 10; PDCD10; programmed cell death 10; programmed cell death protein 10; TF-1 cell apoptosis-related protein 15; Tfa15; TFAR15
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11235
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.6 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q9BUL8
• Gene Symbols: Pdcd10
• Immunogen: Full length fusion protein of Human PDCD10.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG