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PD146176, MedChemExpress

Product Code. 16436527
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Quantity:
5 mg
Unit Size:
5mg
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Product Code. 16436527

Brand: Medchem Express HY103157

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Description

MedChemExpress PD146176 (NSC168807), a 15-Lipoxygenase (15-LO) inhibitor, inhibits rabbit reticulocyte 15-LO (Ki=197 nM, IC50=0.54 μM). PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice.

PD146176 (NSC168807), a 15-Lipoxygenase (15-LO) inhibitor, inhibits rabbit reticulocyte 15-LO (Ki=197 nM, IC50=0.54 μM). PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice.

Specifications

Chemical Name or Material PD146176
CAS 4079-26-9
Color Brown
Purity Grade Notes Research
Molecular Formula C15H11NS
Quantity 5 mg
Synonym NSC168807
Solubility Information DMSO : 25 mg/mL (105.34 mM; Need ultrasonic)
SMILES C1(N2)=C(CSC3=CC=CC=C31)C4=C2C=CC=C4
Molecular Weight (g/mol) 237.32
Formula Weight 237.32
Percent Purity 98.04%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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