PD-1H Armenian Hamster anti-Mouse, PerCP-eFluor 710, Clone: MH5A, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-5919-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15579316

Quantity Price
1 £ 207.27 / 100µg
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Species Reactivity Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL
Clone MH5A
Antigen PD-1H
Format Conjugated
Host Species Armenian Hamster
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Gene Alias VISTA
Quantity 100μg
Isotype IgG
Primary or Secondary Primary
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Conjugate PerCP-eFluor 710

The monoclonal antibody MH5A reacts with a homolog of PD-1 (PD-1H) also known as VISTA. PD-1H is a 309 aa type I transmembrane protein that belongs to the CD28 superfamily. This cell surface receptor is expressed on nearly all hematopoietic cells except B cells. VISTA negatively regulates T cell responses by suppressing early TCR activation, inhibiting cell proliferation, and suppressing TH1 cytokine production.

The MH5A antibody has been reported to inhibit T cell infiltration in graft-versus-host disease mouse models.