PD-1H Armenian Hamster anti-Mouse, Clone: MH5A, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-5919-85

500UG Anti-Mouse PD-1H Functional Grade Purified

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15507796

Quantity Price
1 £ 437.0 / 500µg
Estimated Shipment date
from Supplier 13-12-2016
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Description and Specification

Specification

Antigen PD-1H
Applications Flow Cytometry
Clone MH5A
Concentration 1mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, no sodium azide
Gene Alias VISTA
Host Species Armenian Hamster
Isotype IgG
Quantity 500μg
Regulatory Status RUO
Species Reactivity Mouse
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The monoclonal antibody MH5A reacts with a homolog of PD-1 (PD-1H) also known as VISTA. PD-1H is a 309 aa type I transmembrane protein that belongs to the CD28 superfamily. This cell surface receptor is expressed on nearly all hematopoietic cells except B cells. VISTA negatively regulates T cell responses by suppressing early TCR activation, inhibiting cell proliferation, and suppressing TH1 cytokine production.

The MH5A antibody has been reported to inhibit T cell infiltration in graft-versus-host disease mouse models.