Invitrogen™ PCSK9 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA578663

Product Code. 16377354

Description

Positive Control: A431, HeLa, HepG2 Predicted Reactivity: Mouse (82%), Rat (83%), Rhesus Monkey (96%), Chimpanzee (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

Specifications

• Antigen: PCSK9
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PCSK9
• Gene Alias: AI415265; AI747682; convertase subtilisin; convertase subtilisin/kexin type 9 preproprotein; FH3; HCHOLA3; hypercholesterolemia; LDLCQ1; NARC1; NARC-1; neural apoptosis regulated convertase 1; neural apoptosis-regulated convertase 1; OTTHUMP00000009833; PC9; PCSK9; Proprotein convertase 9; proprotein convertase PC9; proprotein convertase subtilisin/kexin type 9; PSEC0052; Subtilisin/kexin-like protease PC9
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 255738
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Western Blot
• Concentration: 0.21 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q8NBP7
• Gene Symbols: PCSK9
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PCSK9. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG