Invitrogen™ PCPTP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA588442

Product Code. 16506691

Description

Immunogen sequence: FSGNNDHFLA INQKKSGKPV FIYKHSQDIE KSLDIAPQKI YRHSYHSSSE AQVSKRHQIV NSAFPRPAYD PSLNLLAMDG QDLEVENLPI PAANVIVVTL QMDVNKLNIT LLRIFRQGVA AALGLLPQQV HINRLIGKKN SIELFVSPIN RKTGISDALP SEEVLRSLNI NVLHQSLSQF GITEVSPEKN VLQGQHEADK IWSKEG Positive Samples: U-87MG, HT-29, Rat heart; Cellular Location: Cell membrane, Cytoplasm, Single-pass type I membrane protein, perinuclear region, perinuclear region.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of this gene was reported to be regulated by the nerve growth factor, which suggested the function of this gene in neuronal growth and differentiation.

Specifications

• Antigen: PCPTP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTPRR
• Gene Alias: Ch-1 PTPase; ch-1PTPase; ECPPT; ECPTP; EC-PTP; Gmcp1; mPTP213; NC-PTPCOM1; PC12-PTP1; PCPTP1; Phosphotyrosine phosphatase 13; protein tyrosine phosphatase Cr1PTPase; protein tyrosine phosphatase PCPTP1; protein tyrosine phosphatase, receptor type R; protein tyrosine phosphatase, receptor type, R; protein-tyrosine phosphatase NC-PTPCOM1; protein-tyrosine phosphatase PCPTP1; Protein-tyrosine-phosphatase SL; protein-tyrosine-phosphatase-SL; Ptp; Ptp13; PTPBR7; PTPRQ; PTPRR; PTP-SL; receptor-type tyrosine-protein phosphatase R; R-PTP-R; RPTPRR; STEP-like PTPase; tyrosine phosphatase CBPTP
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5801, 94202
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.91 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O08617, Q15256
• Gene Symbols: PTPRR
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-227 of human PTPRR (NP_0028402).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG