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PCNA Mouse anti-Human, Clone: PCNA/694, Abnova™
Description
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq]
Specifications
Specifications
| Antigen | PCNA |
| Applications | Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | PCNA/694 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against full length recombinant human PCNA. |
| Dilution | Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be d |
| Formulation | In 10mM PBS (0.05% BSA, 0.05% sodium azide). |
| Gene Alias | MGC8367 |
| Gene Symbols | PCNA |
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