Invitrogen™ PCDHB6 Monoclonal Antibody (2G11)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA522256

Product Code. 15589092

Description

Peptide Sequence: ASLRVRDIND HAPEFPAREM LLKISEITMP GKIFPLKMAH DLDTGSNGLQ RYTISSNPHF HVLTRNRSEG RKFPELVLDK PLDREEQPQL RLTLIALDGG.

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Specifications

• Antigen: PCDHB6
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9Y5E3
• Gene Symbols: PCDHB6
• Immunogen: PCDHB6 (NP_061762, 118 a.a. ~ 217 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot
• Clone: 2G11
• Conjugate: Unconjugated
• Gene: PCDHB6
• Gene Alias: PCDHB6; PCDH-BETA6; PCDH-beta-6; POLR1E; protocadherin beta 6; protocadherin beta-6
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56130
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid