Invitrogen™ PCDHA10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA595891

Product Code. 16558731

Description

Immunogen sequence: PRFSVTEQKL SIPESRLLDS RFPLEGASDA DVGENALLTY KLSPNEYFVL DIINKKDKDK FPVLVLRKLL DREENPQLKL L.

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Specifications

• Antigen: PCDHA10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PCDHA10
• Gene Alias: cadherin-related neuronal receptor 10; cadherin-related neuronal receptor 3; Cnr3; CNR8; CNRN8; CNRS8; Crnr3; CRNR8; KIAA0345-like 4; ortholog to mouse CNR8; Pcdha10; Pcdha14; PCDH-ALPHA10; PCDH-alpha-10; protocadherin alpha 10; protocadherin alpha 14; protocadherin alpha-10; rCNRv10
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56139
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.97 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9Y5I2
• Gene Symbols: PCDHA10
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 130-210 of human PCDHA10 (NP_1140661).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG