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Invitrogen™ PCDH18 Polyclonal Antibody

Product Code. 12808852
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Quantity:
100 μg
Unit Size:
100µg
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12808852 100 μg 100µg
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Product Code. 12808852 Supplier Invitrogen™ Supplier No. PA520704

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Description

Rabbit Polyclonal Antibody

A suggested positive control is HepG2 cell lysate. PA5-20704 can be used with blocking peptide PEP-0819.

Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 18 (PCDH18) was initially identified through screening of human and mouse ESTs using conserved cytoplasmic domain motifs. Tissue screening revealed PCDH18 broad expression in tissues such as brain, liver, heart, kidney, lung, and trachea. PCDH18 expression is also temporally and spatially regulated in the mouse embryonic brain and interacts with Disabled-1, an intracellular adapter protein involved in neuronal migration and cell positioning during mammalian brain development. PCDH18 was also found to be expressed in the developing zebrafish neural tube and central nervous system, lending support to the hypothesis that PCDH18 may play a role during brain development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDH18
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene PCDH18
Gene Accession No. Q8VHR0, Q9HCL0
Gene Alias 3110038E07Rik; BB095589; DKFZP434B0923; Kiaa1562; PCDH18; PCDH68L; Protocadherin 18; protocadherin 68-like protein; protocadherin-18
Gene Symbols PCDH18
Host Species Rabbit
Immunogen A 17 amino acid peptide near the amino terminus of human PCDH18.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 295027, 54510, 73173
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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