Invitrogen™ PCDH15 Polyclonal Antibody

Sheep Polyclonal Antibody

Brand:  Invitrogen™ PA547865

Product Code. 15598352

Description

In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) Protocadherin-1, rhProtocadherin-8, and rhProtocadherin-10 is observed. Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.

Specifications

• Antigen: PCDH15
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PCDH15
• Gene Alias: Ames waltzer; av; BB078305; cadherin-related family member 15; CDHR15; DFNB23; DKFZp667A1711; ENSMUSG00000046980; Gm9815; nmf19; Pcdh15; protocadherin 15; protocadherin 15 CD2; protocadherin 15 CD3 isoform; protocadherin related 15; protocadherin-15; protocadherin-15-CD2; protocadherin-related 15; RP11-449J3.2; USH1F
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 65217
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q96QU1
• Gene Symbols: PCDH15
• Immunogen: CHO-derived recombinant human Protocadherin-15 Gln27-Ala1376.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG