Invitrogen™ PCDH12 Monoclonal Antibody (868909)

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA561886

Product Code. 30533747

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA; further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2, 289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.

Specifications

• Antigen: PCDH12
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and no preservative
• Gene Accession No.: O55134
• Gene Symbols: PCDH12
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Protocadherin-12, Met1-Ala716.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 868909
• Conjugate: Unconjugated
• Gene: PCDH12
• Gene Alias: Pcdh12; Pcdh14; protocadherin 12; protocadherin 14; protocadherin-12; Protocadherin-12, secreted form; UNQ395/PRO731; Vascular cadherin-2; vascular endothelial cadherin 2; vascular endothelial cadherin-2; VECAD2; VE-cad-2; VE-cadherin 2; VE-cadherin-2
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 53601
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized