Invitrogen™ PCDH1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA584011

Product Code. 16340965

Description

Immunogen sequence: TRVVYKVPEE QPPNTLIGSL AADYGFPDVG HLYKLEVGAP YLRVDGKTGD IFTTETSIDR EGLRECQNQL PGDPCILEFE VSITDLVQN Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 94%.

Protocadherin 1, also known as PCDH1 and cadherin-like protein 1, is a transmembrane protein involved in cell-cell adhesion. Protocadherin 1 belongs to a group of cadherin-like proteins termed delta1-protocadherins, which consists of protocadherin-1, -7, -9, and -11(X/Y). The delta1-protocadherins have seven extracellular cadherin-repeats, a transmembrane domain, and a cytoplasmic domain, and can be expressed in two isoforms, short or long. Expression of protocadherin 1 is regulated both temporally and spatially, and plays a role both in early development and mature tissues. In mice, it is expressed in a number of tissues and organs, including the brain, spinal cord, peripheral ganglia, inner ear, hair follicles, kidney, reproductive organs, prostate, and the seminal gland. Notably, protocadherin 1 is a susceptibility gene for Bronchial Hyperresponsiveness in humans. Expression of protocadherin 1 has also been identified on human pluripotent stem cells.

Specifications

• Antigen: PCDH1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PCDH1
• Gene Alias: 2010005A06Rik; AI585920; cadherin-like 1; cadherin-like protein 1; PC42; PCDH1; PCDH42; protocadherin 1; protocadherin 1 (cadherin-like 1); protocadherin 42; protocadherin-1; Protocadherin-42
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5097
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q08174
• Gene Symbols: PCDH1
• Immunogen: Recombinant protein corresponding to Human PCDH1. Recombinant protein control fragment (Product #RP-98501).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG