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Invitrogen™ PCBP4 Polyclonal Antibody

Product Code. 12858542
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Quantity:
100 μg
Unit Size:
100µg
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12858542 100 μg 100µg
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Product Code. 12858542 Supplier Invitrogen™ Supplier No. PA520359

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Description

Rabbit Polyclonal Antibody

A suggested positive control is Hela cell lysate. PA5-20359 can be used with blocking peptide PEP-0479.

MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in the suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, leading to speculation that MCG10 can act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCBP4
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene PCBP4
Gene Accession No. P57723
Gene Alias 1200003L19Rik; alpha CP-4; alpha-CP4; AlphaCP-4; alphaCP-4 protein; CBP; LIP4; LYST-interacting protein; MCG10; Pcbp4; poly(rC) binding protein 4; poly(rC)-binding protein 4; RNA binding protein MCG10
Gene Symbols PCBP4
Host Species Rabbit
Immunogen A 17 amino acid peptide from near the carboxy terminus of human MCG10.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57060
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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