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PCBP2 Recombinant Rabbit Monoclonal Antibody (JE65-05), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen MA544699

Additional Details : Weight : 0.01000kg

Product Code. 17838592

  • £383.00 / 100µL
Estimated Shipment: 19-08-2024
to see stock.

Description

Description

The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. This gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

PCBP2
Recombinant Monoclonal
1 mg/mL
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Q15366, Q61990
PCBP2
Synthetic peptide within human PCBP2 aa 251-300/365.
100 μL
Primary
Human, Mouse
Liquid
Immunohistochemistry (Paraffin), Western Blot
JE65-05
Unconjugated
PCBP2
Alpha CP2; Alpha-CP2; alphaCP-2; AW412548; CBP; CTBP; fb36h02; Heterogeneous nuclear ribonucleoprotein E2; heterogeneous nuclear ribonucleoprotein X; heterogenous nuclear ribonucleoprotein E2; hnRNP E2; hnRNP X; HNRNPE2; hnRNP-E2; Hnrnpx; HNRPE2; Hnrpx; MGC110998; Pcbp2; pcbp2 protein; PCBP3; poly(rC) binding protein 2; poly(rC)-binding protein 2; Putative heterogeneous nuclear ribonucleoprotein X; rCbinding protein 2; wu:fb36h02; zgc:55964
Rabbit
Protein A
RUO
18521, 5094
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
IgG
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