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Tocris Bioscience™ Paxilline
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Product Code. 30001306
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Quantity:
10 mg
Unit Size:
10mg
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Product Code. 30001306

Brand: Tocris Bioscience™ 2006/10

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This item is not returnable. View return policy

Description

SERCA ATPase blocker. Also potent BKCa channel blocker

Potent blocker of high-conductance Ca2+-activated K+ (BKCa, KCa1.1) channels. Binds to the α-subunit of BKCa (Ki = 1.9 nM for block of currents in α-subunit-expressing oocytes) and enhances binding of charybdotoxin to BKCa channels in vascular smooth muscle. Also inhibits sarco/endoplasmic reticulum Ca2+-ATPase (IC50 = 5 - 50 μM).
TRUSTED_SUSTAINABILITY

Specifications

CAS 57186-25-1
Quantity 10 mg
Molecular Formula C27H33NO4
Formula Weight 435.56
Purity >98%
Molecular Weight (g/mol) 435.564
Chemical Name or Material Paxilline
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