Paxilline, 97+%, Thermo Scientific Chemicals

Product Code. 15433949

Brand: Thermo Scientific Alfa Aesar J61341.#0

Description

Potent blocker of high-conductance calcium-activated potassium (BKCa) channels

Potent blocker of high-conductance calcium-activated potassium (BKCa) channels

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

• CAS: 57186-25-1
• Molecular Formula: C27H33NO4
• Molecular Weight (g/mol): 435.564
• MDL Number: MFCD00083464
• InChI Key: ACNHBCIZLNNLRS-UBGQALKQSA-N
• Synonym: paxilline, unii-3t9u9z96l7, 2h-1-benzopyrano 5',6':6,7 indeno 1,2-b indol-3 4bh-one, 5,6,6a,7,12,12b,12c,13,14,14a-decahydro-4b-hydroxy-2-1-hydroxy-1-methylethyl-12b,12c-dimethyl-, 2-alpha,4b-beta,6a-alpha,12b-beta,12c-alpha,14a-beta, 2h-pyrano 2,3:5',6' benz 1',2':6,7 indeno 1,2-b indol-3 4bh-one, 5,6,6a,7,12,12b,12c,13,14,14a-decahydro-4b-hydroxy-2-1-hydroxy-1-methylethyl-12b,12c-dimethyl-, 2r,4bs,6as,12bs,12cr,14as, spectrum5_001975, paxilline, powder hplc, paxilline solution, 100 mug/ml in acetonitrile, analytical standard, 2r,4bs,6as,12bs,12cr,14as-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-4b-hydroxy-2-1-hydroxy-1-methylethyl-12b,12c-dimethyl-2h-pyrano 2,3:5',6' benz 1',2':6,7 indeno 1,2-b indol-3 4bh-one, ncgc00025342-07_c27h33no4_ 2r,4bs,6as,12bs,12cr,14as-4b-hydroxy-2-2-hydroxy-2-propanyl-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2h-chromeno 5',6':6,7 indeno 1,2-b indol-3 4bh-one
• PubChem CID: 105008
• ChEBI: CHEBI:34907
• SMILES: CC12CCC3C(=CC(=O)C(O3)C(C)(C)O)C1(CCC4C2(C5=C(C4)C6=CC=CC=C6N5)C)O

• Color: White to Yellow
• Quantity: 5 mg
• UN Number: UN2811
• Solubility Information: Soluble in DMSO,acetone or chloroform.
• Formula Weight: 435.56
• Percent Purity: ≥97%
• Physical Form: Powder
• Chemical Name or Material: Paxilline

Safety and Handling

Product Identifier

• Paxilline

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 2
• Acute toxicity Category 3
• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H301-Toxic if swallowed.
• H311-Toxic in contact with skin.
• H315-Causes skin irritation.
• H318-Causes serious eye damage.
• H330-Fatal if inhaled.
• H335-May cause respiratory irritation.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.
• P332+P313-If skin irritation occurs: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : Paxilline from Penicillium paxilli

SDS

RUO – Research Use Only