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DiscoverX PathHunter™ U2OS IL10RA/IL10RB Dimerization Cell Line

Product Code. 17314159
Encompass
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Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17314159

Brand: DiscoverX 930985C3

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This item is not returnable. View return policy

Description

The PathHunter™ U2OS IL10RA/IL10RB Dimerization Cell Line measures ligand-induced dimerization of IL10RA/IL10RB . This cell line ships as two vials of cryopreserved cells.

The PathHunter™ IL10RA/IL10RB Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. IL-10) induced dimerization of IL10RA/IL10RB receptors. This product uses EFC technology. The cell line included overexpresses IL10RA target protein fused to PK alongside IL10RB target protein fused to EA. Upon ligand-induced dimerization of IL10RA/IL10RB , detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Dimerization
Cell Line U2OS
For Use With (Application) Cell Lines
Primary Agonist IL-10
Quantity 2 Vials
Target Entry IL10RA/IL10RB
Accession Number NM_001558.3
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