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Invitrogen™ PATE3 Polyclonal Antibody
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Product Code. 15972605
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100 μL
Unit Size:
100µL
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15972605 100 μL 100µL
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Product Code. 15972605 Supplier Invitrogen™ Supplier No. PA576081

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Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

PATE3 (prostate and testis expressed protein 3), also known as PATE-DJ or HEL-127, is a 98 amino acid protein that contains one UPAR/Ly6 domain and belongs to the PATE family. PATE3 is a secreted protein that is expressed in prostate and testis. The gene that encodes PATE3 consists of around 3,490 bases and maps to human chromosome 11p15.5. Chromosome 11, which comprises approximately 4% of the human genome, is considered a gene and disease association-dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PATE3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene PATE3
Gene Accession No. B3GLJ2, B3GLJ3
Gene Alias Acrosomal vesicle protein HEL-127; epididymis-specific ESC112; Gm17365; HEL-127; Pate3; PATE-DJ; PATE-like protein DJ; predicted gene, 17365; prostate and testis expressed 3; prostate and testis expressed DJ; prostate and testis expressed protein 3; secreted TFP/Ly-6/uPAR protein PATE-DJ
Gene Symbols PATE3
Host Species Rabbit
Immunogen Recombinant full length Human PATE3.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100169851, 100312956, 100361414
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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