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Invitrogen™ Parvalbumin Monoclonal Antibody (CL15072)
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Product Code. 30829973
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100 μL
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30829973 100 μL
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Product Code. 30829973 Supplier Invitrogen™ Supplier No. MA563023
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Estimated Shipment: 24-09-2026
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Description

Mouse Monoclonal Antibody

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 94%.

Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Parvalbumin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone CL15072
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Pvalb
Gene Accession No. P02625, P20472, P32848
Gene Alias D22S749; HGNC:9704; MGC116759; PALB1; Parv; parvalbumin; Parvalbumin (calcium binding protein); parvalbumin alpha; PV; Pva; PVALB
Gene Symbols Pvalb
Host Species Mouse
Immunogen Recombinant protein corresponding to Human PVALB.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19293, 25269, 5816
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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