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PARP1 Mouse anti-Human, Clone: HLNC4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-6668-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15297927

  • £152.25 / 100µg


Estimated Shipment
27-10-2017
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Disclaimers:

For Research Use Only.


Description

Description

This HLNC4 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85kDa and 25 kDa.

The HLNC4 antibody specifically recognizes the 85kDa PARP1 fragment produced after cleavage and does not recognize the full-length 116kDa protein.The following peptide was used as the immunogen: NH2-GVDEVAKKKSKKEKDC-COOH.
Specifications

Specifications

PARP1
HLNC4
Unlabeled
Purified
Murine
100μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
poly ADP-ribose polymerase
IgG1
RUO
Primary
Human