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Invitrogen™ PARL Monoclonal Antibody (4F4)

Description
Peptide Sequence: AWRGWAQRGW GCGQAWGASV GGRSCEELTA VLTPPQLLGR RFNFFIQQKC GFRKAPRKVE PRRSDPGTSG EAYKRSALIP PVEETVFYPS PYPIRSLIK.
This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
Specifications
Specifications
| Antigen | PARL |
| Applications | ELISA |
| Classification | Monoclonal |
| Clone | 4F4 |
| Concentration | 0.2-1.0 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | PARL |
| Gene Accession No. | Q9H300 |
| Gene Alias | D16Ertd607e; Mitochondrial intramembrane cleaving protease PARL; mitochondrial intramembrane-cleaving protease PARL; Parl; parl {ECO:0000250; Pbeta; P-beta; presenilin associated rhomboid like; presenilin associated, rhomboid-like; presenilin associated, rhomboid-like isoform 1 preproprotein; presenilin associated, rhomboid-like preproprotein; presenilins-associated rhomboid-like protein, mitochondrial; PRO2207; Psarl; PSARL1; PSENIP2; RHBDS1; rhomboid 7 homolog 1; UniProtKB:Q9H300} |
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