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Invitrogen™ PAOX Polyclonal Antibody

Description
PAOX Polyclonal Antibody for Western Blot, IHC (P)
Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380). Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs (PubMed:12477380). [UniProt].
Specifications
Specifications
| Antigen | PAOX |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | Paox |
| Gene Accession No. | Q6QHF9 |
| Gene Alias | 2410012F02Rik; AI118225; exo-N4-amino; PAO; Paox; Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N1-acetyl-spermine/spermidine oxidase; polyamine oxidase; polyamine oxidase (exo-N4-amino); polyamine oxidase (exo-N4-amino) isoform 1; putative GTP-binding protein; UNQ1923/PRO4398 |
| Gene Symbols | Paox |
| Show More |
Product Title
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