Invitrogen™ PAOX Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA525758

Product Code. 13249398

Description

PAOX Polyclonal Antibody for Western Blot, IHC (P)

Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380). Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs (PubMed:12477380). [UniProt].

Specifications

• Antigen: PAOX
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Paox
• Gene Alias: 2410012F02Rik; AI118225; exo-N4-amino; PAO; Paox; Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N1-acetyl-spermine/spermidine oxidase; polyamine oxidase; polyamine oxidase (exo-N4-amino); polyamine oxidase (exo-N4-amino) isoform 1; putative GTP-binding protein; UNQ1923/PRO4398
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 196743, 212503
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q6QHF9, Q8C0L6
• Gene Symbols: Paox
• Immunogen: KLH conjugated synthetic peptide between 467-496 amino acids from the central region of human PAOX.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG