Invitrogen™ PAM Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5115606

Product Code. 17288383

Description

Antibody detects endogenous levels of total MYCBP2.

This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect.

Specifications

• Antigen: PAM
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYCBP2
• Gene Alias: AU023734; AW107953; AW546647; C130061D10Rik; E3 ubiquitin-protein ligase MYCBP2; Highwire; KIAA0916; MYC binding protein 2; MYC binding protein 2, E3 ubiquitin protein ligase; Myc-binding protein 2; Mycbp2; Myc-bp2; PAM; pam, highwire, rpm 1; pam/highwire/rpm-1 protein; Phr; Phr1; probable E3 ubiquitin-protein ligase MYCBP2; protein associated with Myc; Protein Magellan; R75243
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 105689, 23077, 290447
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O75592, Q7TPH6
• Gene Symbols: MYCBP2
• Immunogen: A synthesized peptide derived from human MYCBP2(Accession O75592), corresponding to amino acid residues S979-E1029.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG