Palbociclib monohydrochloride, MedChemExpress

Product Code. 16401326

Brand: Medchem Express HY50767A

Description

MedChemExpress Palbociclib (PD 0332991) monohydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib monohydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

Palbociclib (PD 0332991) monohydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib monohydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

Specifications

• Chemical Name or Material: Palbociclib monohydrochloride
• CAS: 827022-32-2
• Color: Yellow
• Purity Grade Notes: Research
• Molecular Formula: C₂₄H₃₀ClN₇O₂
• Quantity: 200 mg
• Synonym: PD 0332991 monohydrochloride
• Solubility Information: H2O : 7.14 mg/mL (14.75 mM; ultrasonic and warming and heat to 60°C) ∣DMSO : 4.63 mg/mL (9.57 mM; ultrasonic and warming and heat to 80°C)
• SMILES: O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCNCC4)C=C3)N=C2N1C5CCCC5.Cl
• Molecular Weight (g/mol): 483.99
• Formula Weight: 483.99
• Percent Purity: 95.0%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-Kinase/protease

Research purposes only