Palbociclib, MedChemExpress

Product Code. 16420568

Brand: Medchem Express HY50767

Description

MedChemExpress Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

Specifications

• Chemical Name or Material: Palbociclib
• CAS: 571190-30-2
• Color: Yellow
• Purity Grade Notes: Research
• Molecular Formula: C₂₄H₂₉N₇O₂
• Quantity: 5 mg
• Synonym: PD 0332991
• Solubility Information: DMSO : 25 mg/mL (55.86 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C) ∣0.1 M HCL : 25 mg/mL (55.86 mM; ultrasonic and adjust pH to 4 with 0.1 M HCL) ∣H2O : 0.1 mg/mL (0.22 mM; Need ultrasonic)
• SMILES: O=C1C(C(C)=O)=C(C2=CN=C(N=C2N1C3CCCC3)NC4=CC=C(N5CCNCC5)C=N4)C
• Molecular Weight (g/mol): 447.53
• Formula Weight: 447.53
• Percent Purity: 95.0%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-Kinase/protease

Research purposes only