Invitrogen™ PACSIN1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA584257

Product Code. 16301215

Description

Immunogen sequence: EKQPKKAEGV ALTNATGAVE STSQAGDRGS VSSYDRGQPY ATEWSDDESG N Highest antigen sequence indentity to the following orthologs: Mouse - 92%, Rat - 94%.

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Specifications

• Antigen: PACSIN1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pacsin1
• Gene Alias: A830061D09Rik; Dynamin PRD-interacting protein; dynamin proline-rich domain-interacting protein; H74; KIAA1379; mKIAA1379; Pacsin; Pacsin1; protein kinase C and casein kinase substrate in neurons 1; protein kinase C and casein kinase substrate in neurons protein 1; SdpI; synaptic, dynamin-associated protein I; syndapin; syndapin 1; syndapin I; syndapin-1; Syndapin-I
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29993
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BY11
• Gene Symbols: Pacsin1
• Immunogen: Recombinant protein corresponding to Human PACSIN1. Recombinant protein control fragment (Product #RP-101745).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG