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Pacritinib, MedChemExpress

Product Code. 16403097
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Product Code. 16403097

Brand: Medchem Express HY16379

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MedChemExpress Pacritinib (SB1518) is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). Pacritinib also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM).

Pacritinib (SB1518) is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). Pacritinib also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM).

Specifications

Chemical Name or Material Pacritinib
CAS 937272-79-2
Color Yellow
Purity Grade Notes Research
Molecular Formula C28H32N4O3
Quantity 50 mg
Synonym SB1518
Solubility Information DMSO : 5 mg/mL (10.58 mM; Need ultrasonic)
SMILES C1(COC/C=C/COCC2=C(OCCN3CCCC3)C=CC4=C2)=CC=CC(C5=N/C(NC=C5)=N\4)=C1
Molecular Weight (g/mol) 472.58
Formula Weight 472.58
Percent Purity 98.21%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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