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PAC 1, Tocris Bioscience™
Activator of procaspase-3; pro-apoptotic
£152.72 - £581.00
Chemical Identifiers
| CAS | 315183-21-2 |
|---|---|
| Molecular Formula | C23H28N4O2 |
| Molecular Weight (g/mol) | 392.50 |
| MDL Number | MFCD03302441 |
| InChI Key | XSGXRYNZNGUGEJ-UHFFFAOYSA-N |
| Synonym | pac-1, procaspase-3 activator, procaspase activating compound 1, procaspase-3 activator, pac-1, 4-benzylpiperazino acetic acid-3-allyl-2-hydroxybenzylidene hydrazide, 2-4-benzylpiperazin-1-yl-n'-z-6-oxo-5-prop-2-enylcyclohexa-2,4-dien-1-ylidene methyl acetohydrazide, d01yif, e-n'-3-allyl-2-hydroxybenzylidene-2-4-benzylpiperazin-1-yl acetohydrazide, 2-4-benzylpiperazin-1-yl-n'-1e-2-hydroxy-3-prop-2-en-1-yl phenyl methylidene acetohydrazide, 4-phenylmethyl-1-piperazineacetic acid 2-hydroxy-3-2-propenyl phenyl methylene hydrazide |
| PubChem CID | 6851947 |
| IUPAC Name | 2-(4-benzylpiperazin-1-yl)-N'-{[6-oxo-5-(prop-2-en-1-yl)cyclohexa-2,4-dien-1-ylidene]methyl}acetohydrazide |
| SMILES | C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC3=CC=CC=C3)CC2)C1=O |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18065592
|
Tocris Bioscience
2581/10 |
10 mg |
£152.72
10mg |
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|
18014412
|
Tocris Bioscience
2581/50 |
50 mg |
£581.00
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Procaspase-activating compound; activates procaspase-3 to produce caspase-3 (EC50 = 0.22 μM). Also activates procaspase-7 in a less efficient manner (EC50 = 4.5 μM). Pro-apoptotic; induces apoptosis in both cancerous and non-cancerous cells dependent on procaspase-3 concentration (IC50 values are 0.003 - 1.41 and 5.02 - 9.98 μM respectively).Chemical Identifiers
| 315183-21-2 | |
| 392.50 | |
| XSGXRYNZNGUGEJ-UHFFFAOYSA-N | |
| 6851947 | |
| C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC3=CC=CC=C3)CC2)C1=O |
| C23H28N4O2 | |
| MFCD03302441 | |
| pac-1, procaspase-3 activator, procaspase activating compound 1, procaspase-3 activator, pac-1, 4-benzylpiperazino acetic acid-3-allyl-2-hydroxybenzylidene hydrazide, 2-4-benzylpiperazin-1-yl-n'-z-6-oxo-5-prop-2-enylcyclohexa-2,4-dien-1-ylidene methyl acetohydrazide, d01yif, e-n'-3-allyl-2-hydroxybenzylidene-2-4-benzylpiperazin-1-yl acetohydrazide, 2-4-benzylpiperazin-1-yl-n'-1e-2-hydroxy-3-prop-2-en-1-yl phenyl methylidene acetohydrazide, 4-phenylmethyl-1-piperazineacetic acid 2-hydroxy-3-2-propenyl phenyl methylene hydrazide | |
| 2-(4-benzylpiperazin-1-yl)-N'-{[6-oxo-5-(prop-2-en-1-yl)cyclohexa-2,4-dien-1-ylidene]methyl}acetohydrazide |
Specifications
| 315183-21-2 | |
| MFCD03302441 | |
| XSGXRYNZNGUGEJ-UHFFFAOYSA-N | |
| 2-(4-benzylpiperazin-1-yl)-N'-{[6-oxo-5-(prop-2-en-1-yl)cyclohexa-2,4-dien-1-ylidene]methyl}acetohydrazide | |
| 6851947 | |
| >98% |
| C23H28N4O2 | |
| pac-1, procaspase-3 activator, procaspase activating compound 1, procaspase-3 activator, pac-1, 4-benzylpiperazino acetic acid-3-allyl-2-hydroxybenzylidene hydrazide, 2-4-benzylpiperazin-1-yl-n'-z-6-oxo-5-prop-2-enylcyclohexa-2,4-dien-1-ylidene methyl acetohydrazide, d01yif, e-n'-3-allyl-2-hydroxybenzylidene-2-4-benzylpiperazin-1-yl acetohydrazide, 2-4-benzylpiperazin-1-yl-n'-1e-2-hydroxy-3-prop-2-en-1-yl phenyl methylidene acetohydrazide, 4-phenylmethyl-1-piperazineacetic acid 2-hydroxy-3-2-propenyl phenyl methylene hydrazide | |
| C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC3=CC=CC=C3)CC2)C1=O | |
| 392.50 | |
| 392.5 | |
| PAC 1 |
Safety and Handling
Recommended Storage : Store at +4°C