Invitrogen™ PABP Monoclonal Antibody (10E10)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA134079

Product Code. 11594063

Description

MA1-34079 detects PABP from human, chicken, rabbit and Xenopus laevis samples. Does not react wtih Drosophilia melanogaster or mouse samples.

The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4), and PABP3 (PABPC3). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.

Specifications

• Antigen: PABP
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P11940, P20965
• Gene Symbols: PABPC1, pabpc1.S
• Immunogen: Recombinant PABP (Human) expressed from its 1.85 kbp cDNA, NcoI to SspI.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Rabbit, Chicken, Frog
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 10E10
• Conjugate: Unconjugated
• Gene: PABPC1
• Gene Alias: Cytoplasmic poly(A)-binding protein 1-A; ePAB; hypothetical protein; PAB1; pabp; PABP 1; Pabp1; PABP-1; PABP-1A; PABP-1-A; PABP-A; Pabpc1; pabpc1.L; pabpc1.S; pabpc1a; pabpc1-a; pabpc1a protein; pabpc1-b; pabpc2; PabpI; PABPL1; poly A binding protein 1; poly A binding protein, cytoplasmic 1 a; poly(A) binding protein cytoplasmic 1; poly(A) binding protein, cytoplasmic 1; poly(A) binding protein, cytoplasmic 1 L homeolog; poly(A) binding protein, cytoplasmic 1 S homeolog; poly(A) binding protein, cytoplasmic 1a; poly(A) binding protein, cytoplasmic 2; poly(A)-binding protein 1; poly(A)-binding protein 1A; poly(A)-binding protein 1-A; polyadenylate-binding protein 1; Polyadenylate-binding protein 1A; Polyadenylate-binding protein 1-A; polyadenylate-binding protein 1A; poly(A) binding protein, cytoplasmic 1a; wu:fb16a02; wu:fi19b08; wu:fj12d09; wu:fj61f06; XELAEV_18033915mg; xPABP1-A; zgc:109879
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100342434, 26986, 379896, 430997
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid