Invitrogen™ P4HA2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA555704

Product Code. 15773621

Description

Immunogen sequence: LDYLSYAVFQ LGDLHRALEL TRRLLSLDPS HERAGGNLRY FEQLLEEERE KTLTNQTEAE LATPEGIYER PVDYLPERDV YESLCRGEGV KLTPRRQKRL FCRYHHGNRA PQLLIAPFKE EDEWDSPHIV RYYDVMS Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 90%.

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: P4HA2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: P4HA2
• Gene Alias: 4-PH alpha 2; 4-PH alpha-2; 4PHalpha2; AA407196; C76437; collagen prolyl 4-hydroxylase alpha(II); C-P4Halpha(II); hypothetical protein LOC507327; P4HA2; P4hl; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II; procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2; prolyl 4-hydroxylase A; Prolyl 4-hydroxylase alpha IIa subunit; prolyl 4-hydroxylase subunit alpha 2; prolyl 4-hydroxylase subunit alpha-2; prolyl 4-hydroxylase, alpha polypeptide II; UNQ290/PRO330; zgc:91948
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8974
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O15460
• Gene Symbols: P4HA2
• Immunogen: Recombinant protein corresponding to Human P4HA2. Recombinant protein control fragment (Product #RP-89682).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG