Invitrogen™ p400 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA553475

Product Code. 15761411

Description

Immunogen sequence: DDEVDDEEET IEEEEANEGV VDHQTELSNL AKEAELPLLD LMKLYEGAFL PSSQWPRPKP DGEDTSGEED ADDCPGDRES RKDLVLIDSL FIMDQFKAAE RMNIGKPNAK DIADVTAVAE AILPKGSARV TTSVKFNAPS L Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 84%.

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity.

Specifications

• Antigen: p400
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EP400
• Gene Alias: 1700020J09Rik; AU023439; CAG repeat protein 32; CAGH32; Domino homolog; E1A binding protein p400; E1A-binding protein p400; EP400; hDomino; KIAA1498; KIAA1818; mDomino; mKIAA1498; P400; p400 kDa SWI2/SNF2-related protein; p400 SWI2/SNF2-related protein; TNRC12; trinucleotide repeat containing 12; trinucleotide repeat-containing gene 12 protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57634
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96L91
• Gene Symbols: EP400
• Immunogen: Recombinant protein corresponding to Human p400. Recombinant protein control fragment (Product #RP-91695).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG