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p300 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA1848
Code : NEW
Additional Details : Weight : 0.01000kg
Description
PA1-848 detects p300 from human cells. PA1-848 has been successfully used in Western blot and ChIP procedures. By Western blot, this antibody detects an ∽265 kDa protein representing p300 from HeLa cell lysate. The PA1-848 immunogen is a synthetic peptide corresponding to residues G(139) T S G P N Q G P T Q S T(151) C in the nuclear factor binding domain of human p300. The PA1-848 immunizing peptide (Cat. # PEP-053) is available for use in neutralization and control experiments.
EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.Specifications
p300 | |
Polyclonal | |
Unconjugated | |
EP300 | |
A430090G16; A730011L11; E1A binding protein p300; E1A-associated protein p300; E1A-binding protein, 300kD; Ep300; Histone acetyltransferase p300; Histone butyryltransferase p300; Histone crotonyltransferase p300; KAT3B; P300; p300 HAT; Protein propionyltransferase p300; RSTS2 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
2033 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
ChIP Assay, Immunocytochemistry, Western Blot | |
1 mg/mL | |
PBS with 1mg/mL BSA and 0.05% sodium azide | |
Q09472 | |
EP300 | |
Synthetic peptide corresponding to residues G(139) T S G P N Q G P T Q S T(151) C in the nuclear factor binding domain of human p300. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |