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  6. p107 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

p107 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16841514 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16841514 20 μL 20µL
16831514 150 μL 150µL
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Product Code. 16841514 Supplier Proteintech Supplier No. 133541AP20UL

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Description

Rabbit Polyclonal Antibody

RB-like 1 is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and RB-like 1 can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that RB-like 1 may also be a tumor suppressor.

Specifications

Antigen p107
Applications Western Blot, Immunoprecipitation
Classification Polyclonal
Concentration 0.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RBL1
Gene Accession No. P28749, Q64701
Gene Alias CP107, p107, PRB1, RBL1, retinoblastoma like 1 (p107), Retinoblastoma like protein 1
Gene Symbols RBL1
Host Species Rabbit
Immunogen p107 Fusion Protein Ag4146
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19650, 5933, 680111
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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