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  6. Invitrogen™ P-cadherin Recombinant Rabbit Monoclonal Antibody (K01_1W36)

Invitrogen™ P-cadherin Recombinant Rabbit Monoclonal Antibody (K01_1W36)

Product Code. 30826953
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30826953 100 μL
30827440 50 μL
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Product Code. 30826953 Supplier Invitrogen™ Supplier No. MA563337

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Description

Rabbit Recombinant Monoclonal Antibody

P-cadherin Recombinant Monoclonal Antibody for ICC/IF, IHC (P), Western Blot

P-cadherin, also known as Cadherin-3, is a Type 1 cadherin protein that belongs to the cadherin superfamily. Type 1 cadherins are single-pass transmembrane proteins that have 5 extracellular cadherin repeats and an intracellular domain that binds p120-catenin and beta-catenin. Cadherins are calcium-dependent cell-cell adhesion glycoproteins responsible for a range of processes including development, wound healing, cell-cell signaling, cell growth and differentiation. P-cadherin is expressed in human fetal structures, and in adult tissues such as the basal layer of the epidermis, breast, prostate, ovary, cervix, hair follicle, and corneal endothelium. P-cadherin expression has also been reported on embryonic stem cells, and stem cells of the normal mammary gland, and hair follicle. Overexpression of P-cadherin has been associated with poor prognosis in breast, prostate, ovary, colon, and stomach carcinomas. Mutations in CDH3 are associated with congential hypotrichosis with juvenile macular dystrophy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen P-cadherin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone K01_1W36
Concentration 0.20 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 40% glycerol, 150mM NaCl, 0.05% BSA and 0.01% sodium azide; pH 7.4
Gene Cdh3
Gene Accession No. P10287, P22223
Gene Alias AI385538; CADH3; cadherin 15, M-cadherin (myotubule); cadherin 3; cadherin 3, type 1, P-cadherin (placental); cadherin-3; Cadp; calcium-dependent adhesion protein, placental; CDH3; CDHP; HJMD; PCAD; P-cadherin; Placental cadherin; Placental-cadherin; RPE-specific cadherin
Gene Symbols Cdh3
Host Species Rabbit
Immunogen A synthetic peptide of human pan Cadherin.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1001, 116777, 12560
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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