Oxytetracycline hydrochloride, Thermo Scientific™

Impairs mitochondrial protein synthesis

Brand:  Thermo Scientific Alfa Aesar J62489.14

Product Code. 15464869

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome- lysosome (P-L) fusion in P388D1 cells1 and antibiotic susceptibilities of Mycoplasma bovis isolates.

Solubility
Soluble in ethanol

Notes
Concentrated aqueous solutions at neutral pH will hydrolyze oxytetracycline and cause it to precipitate

Chemical Identifiers

• CAS: 2058-46-0
• Molecular Weight (g/mol): 496.897
• InChI Key: UTAHTGPLLFLKGW-IFLJXUKPSA-N
• IUPAC Name: (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,11,12a-hexahydroxy-6-methyl-1,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride

• Molecular Formula: C22H25ClN2O9
• MDL Number: MFCD00135815
• PubChem CID: 121235537
• SMILES: CC1(C2C(C3C(C(=C(C(=O)C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)C(=O)N)O)N(C)C)O)O.Cl

Specifications

• CAS: 2058-46-0
• Quantity: 25g
• Molecular Formula: C22H25ClN2O9
• Beilstein: 3853107
• Solubility Information: Soluble in ethanol
• SMILES: CC1(C2C(C3C(C(=C(C(=O)C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)C(=O)N)O)N(C)C)O)O.Cl
• Molecular Weight (g/mol): 496.897
• Formula Weight: 496.9

• Color: Gray to Yellow
• Sensitivity: Air and light sensitive
• MDL Number: MFCD00135815
• Merck Index: 14,6976
• InChI Key: UTAHTGPLLFLKGW-IFLJXUKPSA-N
• IUPAC Name: (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,11,12a-hexahydroxy-6-methyl-1,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
• PubChem CID: 121235537
• Chemical Name or Material: Oxytetracycline hydrochloride

Safety and Handling

Product Identifier

• Oxytetracycline hydrochloride

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Reproductive toxicity Category 2

Hazard Statement

• H319-Causes serious eye irritation.
• H361d-Suspected of damaging the unborn child.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P308+P313-IF exposed or concerned: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : Oxytetracycline hydrochloride