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Invitrogen™ OXPAT Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5117687

Artikelnummer. 17260184

  • £466.00 / 100µg

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Beskrivelse

Beskrivelse

This antibody has been tested in direct-ELISA.

Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE.
TRUSTED_SUSTAINABILITY
Tekniske data

Tekniske data

OXPAT
Polyclonal
Unconjugated
Plin5
2310076L09Rik; AI415325; AW109675; lipid droplet associated protein; lipid droplet-associated protein PAT-1; Lipid storage droplet protein 5; LSDA5; LSDP5; Mldp; Myocardial LD protein; Oxpat; Pat1; PAT-1; perilipin 5; perilipin-5; Plin5
Rabbit
Antigen Affinity Chromatography, Protein G
RUO
440503, 66968
-20°C or -80°C if preferred
Liquid
Immunohistochemistry (Paraffin), Western Blot
3 mg/mL
PBS with 50% glycerol and 0.03% ProClin 300, 0.02% sodium azide; pH 7.4
Q00G26, Q8BVZ1
Plin5
Recombinant Human Perilipin-5 protein (305-453aa).
100 μg
Primary
Human, Mouse
Antibody
IgG
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