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OX40L Monoclonal Antibody (OX89), PE, Invitrogen™
Rat Monoclonal Antibody
Brand: Invitrogen MA517913
Code : NEW
Additional Details : Weight : 0.01000kg
Description
MA5-17913 targets CD134L/OX40L in FACS, FN, and IHC applications and shows reactivity with Mouse samples. The MA5-17913 immunogen is cD4.CD134L chimeric protein.
The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.Specifications
OX40L | |
Monoclonal | |
0.1 mg/mL | |
PBS with 4-5mg/mL BSA and 0.02% sodium azide | |
P43488 | |
Tnfsf4 | |
CD4.CD134L chimeric protein | |
50 μg | |
Primary | |
Mouse | |
Antibody | |
IgG1 |
Flow Cytometry | |
OX89 | |
PE | |
Tnfsf4 | |
Ath1; Ath-1; atherosclerosis 1; CD134 ligand; CD134L; CD252; glycoprotein Gp34; GP34; OX40 antigen ligand; OX40 ligand; OX40L; OX-40L; OX4OL; TAX transcriptionally-activated glycoprotein 1; tax-transcriptionally activated glycoprotein 1 (34kD); tax-transcriptionally activated glycoprotein 1 ligand; TNFSF4; TNLG2B; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor (ligand) superfamily, member 4; tumor necrosis factor ligand 2B; tumor necrosis factor ligand superfamily member 4; tumor necrosis factor superfamily member 4; TXGP1; Txgp1l | |
Rat | |
Protein G | |
RUO | |
22164 | |
4° C, do not freeze | |
Liquid |