OVCA2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16883864	Proteintech 14943-1-AP-20UL	20 μL
16873864	Proteintech 14943-1-AP-150UL	150 μL

Description

Chromosome 17 is a hotspot for chromosomal aberrations in breast and ovarian cancer. Candidate oncogenes and tumor suppressors located on this chromosome include OVCA1 and OVCA2, p53, BRCA1, HER2/neu and others. OVCA1 and 2 map to a highly conserved region on human chromosome 17p13.3 that is deleted in 80% of ovarian cancers and shows frequent loss of heterozygosity in breast cancers. OVCA1 is induced by BRCA1 and is closely linked to p53, a well-known tumor suppressor gene. The close linkage of OVCA1 and p53 suggests that coordinated loss of the two genes may lead to ovarian, breast and other tumor types.

Specifications

• Antigen: OVCA2
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Rat, Mouse
• Gene Accession No.: Q8WZ82, Q9D7E3
• Gene ID (Entrez): 124641, 246257, 497954
• Immunogen: OVCA2 Fusion Protein Ag6744
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: OVCA2

• Concentration: 0.17 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: OVCA2
• Gene Symbols: Ovca2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody