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Osilodrostat, MedChemExpress

Product Code. p-200096690
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Product Code. 16487076

Brand: Medchem Express HY16276100mg

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Description

MedChemExpress Osilodrostat (LCI699) is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM.

Osilodrostat is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat inhibits aldosterone and corticosterone synthesis. Osilodrostat has blood pressure lowering ability. Osilodrostat can be used for research of Cushing syndrome (CS).

Specifications

Chemical Name or Material Osilodrostat
CAS 928134-65-0
Color Light Nude
Purity Grade Notes Research
Molecular Formula C13H10FN3
Quantity 100 mg
Synonym LCI699
Solubility Information DMSO : 250 mg/mL (1100.16 mM; Need ultrasonic) ∣Ethanol : 100 mg/mL (440.06 mM; Need ultrasonic)
SMILES N#CC1=CC=C([C@H]2CCC3=CN=CN32)C(F)=C1
Molecular Weight (g/mol) 227.24
Formula Weight 227.24
Percent Purity 99.04%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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