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OSI-027, MedChemExpress

Product Code. 16496677
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Product Code. 16496677 Supplier Medchem Express Supplier No. HY10423

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Description

MedChemExpress OSI-027 (ASP7486) is a potent, selective, orally active and ATP-competitive mTOR kinase activity inhibitor with an IC50 of 4 nM. OSI-027 targets both mTORC1 and mTORC2 with IC50s of 22 nM and 65 nM, respectively.

OSI-027 (ASP7486) is a potent, selective, orally active and ATP-competitive mTOR kinase activity inhibitor with an IC50 of 4 nM. OSI-027 targets both mTORC1 and mTORC2 with IC50s of 22 nM and 65 nM, respectively.

Specifications

Chemical Name or Material OSI-027
CAS 936890-98-1
Color Yellow
Purity Grade Notes Research
Molecular Formula C21H22N6O3
Quantity 5 mg
Synonym ASP7486
Solubility Information DMSO : 125 mg/mL (307.55 mM; Need ultrasonic)
SMILES O=C([C@H]1CC[C@H](C2=NC(C(N3)=CC4=C3C(OC)=CC=C4)=C5C(N)=NC=NN52)CC1)O
Molecular Weight (g/mol) 406.44
Formula Weight 406.44
Percent Purity 95.75%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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