Invitrogen™ OSGEP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA558914

Product Code. 15796781

Description

Immunogen sequence: FEGSANKIGV GVVRDGKVLA NPRRTYVTPP GTGFLPGDTA RHHRAVILDL LQEALTESGL TSQDIDCIAY TKGP Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that is a member of the peptidase M22 family. Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but it does not cleave desialylated glycoproteins, unglycosylated proteins or glycoproteins that are only N-glycosylated. Though ubiquitously expressed at low levels, highest levels of Osgep are found in liver, skeletal muscle and kidney. OSGEPL1, also known as Qri7, is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.

Specifications

• Antigen: OSGEP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OSGEP
• Gene Alias: 1500019L24Rik; GCPL1; GCPL-1; HAMAP-Rule:MF_03180}; hOSGEP; KAE1; mOsgep; N6-L-threonylcarbamoyladenine synthase; OSGEP; OSGEP1; O-sialoglycoprotease; O-sialoglycoprotein endopeptidase; O-sialoglycoprotein endopeptidase {ECO:0000255; pasteurella haemolytica metalloprotease homolog with glycoprotein substrates/gpc-like protein 1; probable O-sialoglycoprotein endopeptidase; probable tRNA N6-adenosine threonylcarbamoyltransferase; probable tRNA N6-adenosine threonylcarbamoyltransferase {ECO:0000255; probable tRNA threonylcarbamoyladenosine biosynthesis protein Osgep; PRSMG1; Prsmg1/Gcpl1; t(6)A synthase; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP; t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgep {ECO:0000255; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP; tRNA threonylcarbamoyladenosine biosynthesis protein Osgep {ECO:0000255
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55644
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NPF4
• Gene Symbols: OSGEP
• Immunogen: Recombinant protein corresponding to Human OSGEP. Recombinant protein control fragment (Product #RP-98345).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG