Invitrogen™ OSGEP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596691

Product Code. 16509531

Description

Immunogen sequence: MPAVLGFEGS ANKIGVGVVR DGKVLANPRR TYVTPPGTGF LPGDTARHHR AVILDLLQEA LTESGLTSQD IDCIAYTKGP GMGAPLVSVA VVARTVAQLW NKPLVGVNHC IGHIEMGRLI TGATSPTVLY VSGGNTQVIA YSEHRYRIFG ETIDIAVGNC LDRFARVLKI SNDPSPGYNI EQMAKRGKKL VELPYTVKGM DVSFSGILSF IEDVAHRMLA TGECTPEDLC FSLQETVFAM LVEITERAMA HCGSQEALIV GGVGCNVRLQ EMMATMCQER GARLFATDER FCIDNGAMIA QAGWEMFRAG HRTPLSDSGV TQRYRTDEVE VTWRD; Positive Samples: HL-60, Raji, Jurkat, 293T, Mouse heart, Mouse skeletal muscle, Mouse ovary, Rat heart, Rat liver; Cellular Location: Cytoplasm, Nucleus.

Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that is a member of the peptidase M22 family. Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but it does not cleave desialylated glycoproteins, unglycosylated proteins or glycoproteins that are only N-glycosylated. Though ubiquitously expressed at low levels, highest levels of Osgep are found in liver, skeletal muscle and kidney. OSGEPL1, also known as Qri7, is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.

Specifications

• Antigen: OSGEP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OSGEP
• Gene Alias: 1500019L24Rik; GCPL1; GCPL-1; HAMAP-Rule:MF_03180}; hOSGEP; KAE1; mOsgep; N6-L-threonylcarbamoyladenine synthase; OSGEP; OSGEP1; O-sialoglycoprotease; O-sialoglycoprotein endopeptidase; O-sialoglycoprotein endopeptidase {ECO:0000255; pasteurella haemolytica metalloprotease homolog with glycoprotein substrates/gpc-like protein 1; probable O-sialoglycoprotein endopeptidase; probable tRNA N6-adenosine threonylcarbamoyltransferase; probable tRNA N6-adenosine threonylcarbamoyltransferase {ECO:0000255; probable tRNA threonylcarbamoyladenosine biosynthesis protein Osgep; PRSMG1; Prsmg1/Gcpl1; t(6)A synthase; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP; t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgep {ECO:0000255; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP; tRNA threonylcarbamoyladenosine biosynthesis protein Osgep {ECO:0000255
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 290028, 55644, 66246
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.3 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8BWU5, Q9NPF4, Q9WVS2
• Gene Symbols: OSGEP
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human OSGEP (NP_0602771).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG