OSCAR Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5140332

Product Code. 17834850

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: VGPGANVSLR CAGRLRNMSF VLYREGVAAP LQYRHSAQPW ADFTLLGARA PGTYSCYYH

Recently, a novel member of the leukocyte receptor complex (LRC) encoded family has been identified that is expressed specifically in osteoclast (OC). This protein names OC-associated receptor or OSCAR, play critical roles in the regulation of both innate and adaptive immune responses and bone-specific regulator of OC differentiation. Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This protein family plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: OSCAR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OSCAR
• Gene Alias: MGC33613; mOSCAR; mOSCAR-M1; mOSCAR-M2; mOSCAR-M3; ocl178; Oscar; osteoclast associated receptor; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; osteoclast associated, immunoglobulin-like receptor; osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; osteoclast-associated receptor OSCAR; PIGR3; PIgR-3; poly-Ig receptor 3; polymeric immunoglobulin receptor 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 126014
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.2 μg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8IYS5
• Gene Symbols: OSCAR
• Immunogen: Recombinant protein corresponding to Human OSCAR
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG