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  6. Ornithine Decarboxylase (ODC) Ab-1, Mouse Monoclonal Antibody,Lab Vision™ Epredia™

Ornithine Decarboxylase (ODC) Ab-1, Mouse Monoclonal Antibody,Lab Vision™ Epredia™

Product Code. 12671507 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Concentration:
1mg/mL
200μg/mL
Unit Size:
100µL
1mL
200µL
500µL
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Product Code. Quantity Concentration unitSize
12671507 100 μL 200μg/mL 100µL
12681507 500 μL 200μg/mL 500µL
12661507 1 mL 200μg/mL 1mL
12691507 100 μL 1mg/mL 100µL
12601517 200 μL 1mg/mL 200µL
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Product Code. 12671507 Supplier Epredia Supplier No. MS464P0

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Description

Take advantage of a quality product that delivers accurate results with the Epredia™ Ornithine Decarboxylase (ODC) Ab-1, Mouse Monoclonal Antibody.

ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Host Species: Mouse

Clone: MP16-2

Isotype: IgG1

Species Reactivity: Human, Rat, and Mouse. Because epitope of MAb MP16-2 (-IWGPTC-) is present in all known eukaryotic ODC sequences, it should react with ODC from other eukaryotes also.

Epitope: aa 355-360 (-IWGPTC-). It is associated with active site of ODC or a locus in its direct vicinity.

Immunogen: A synthetic hexadecapeptide (KPDEKYYSSSIWGPTC) (aa 345-360) from rat ODC

Molecular Weight: 53kDa

Positive Control: Epithelial cells in normal placenta or prostate CA

Cellular Localization: Cytoplasmic Ab-1 recognizes the native ODC and not the inhibited (labeled with H3-DFMO) enzyme.

Recommended for:

  • Immunohistochemistry (Frozen only)
  • Western Blotting (Not verified)

Note:

USA: RUO; Int'l: RUO

TRUSTED_SUSTAINABILITY

Specifications

Antigen Ornithine Decarboxylase (ODC) Ab-1
Applications Immunohistochemistry (Frozen)
Classification Monoclonal
Clone MP16-2
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen A synthetic hexadecapeptide (KPDEKYYSSSIWGPTC) (aa345-360) from rat ODC
Quantity 100 μL
Regulatory Status RUO
Research Discipline Enzyme
Primary or Secondary Primary
Target Species Human, Mouse, Rat
Form Concentrated
Isotype IgG1
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